01 - Preheat oven to 400°F. Line a baking sheet with parchment paper.
02 - In a skillet over medium heat, cook onion until translucent, about 3 minutes. Add ground beef, garlic powder, salt, and black pepper. Cook until beef is browned, then drain excess fat.
03 - Stir ketchup, yellow mustard, Worcestershire sauce, and pickles into the cooked beef mixture. Remove skillet from heat and allow to cool slightly.
04 - Flatten each biscuit round. Place 1 tablespoon of beef filling and 1/2 tablespoon shredded cheddar into the center, then add one mozzarella cube.
05 - Wrap dough completely around the filling, pinch edges tightly to seal, and shape into a ball. Arrange seam side down on the prepared baking sheet.
06 - Brush each assembled bomb with beaten egg and top with sesame seeds.
07 - Bake for 15 to 18 minutes or until biscuit bombs are golden brown.
08 - Let cool briefly before serving. Enjoy with extra burger sauces if desired.